Autoimmune Regulator Monoclonal / Alexa Fluor 700 / 609930

Product Details
Supplier R&D Systems
Catalog #: IC6184N-100UG (View supplier product page)
Size 100 μg
Price $419.00
Antigen Autoimmune Regulator
Clone 609930
Host Rat
Isotype IgG2a
Conjugate Alexa Fluor 700
Target Species Mouse
Applications ICS
Description Mouse Autoimmune Regulator/AIRE Alexa Fluor® 700-conjugated Antibody
About Autoimmune Regulator and Alexa Fluor 700
Autoimmune Regulator This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra