ATM Monoclonal / Unconjugated / 664703
ATM Monoclonal / Unconjugated / 664703
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | MAB22901-SP (View supplier product page) | |
| Size | 25 μg | |
| Price | $149.00 | |
| Antigen | ATM | |
| Clone | 664703 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ICC | |
| Description | Human ATM Antibody |
About ATM and Purified
| ATM | The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010] |
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Images
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ATM in HeLa Human Cell Line. ATM was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line using Mouse Anti-Human ATM Monoclonal Antibody (Catalog # MAB22901) at 25 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips. |
Citations
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Purified Excitation and Emission Spectra
$149.00
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