Apolipoprotein E Monoclonal / Unconjugated / 395004

Product Details
Supplier R&D Systems
Catalog #: MAB41441-SP (View supplier product page)
Size 25 μg
Price $149.00
Antigen Apolipoprotein E
Clone 395004
Host Rat
Isotype IgG2a
Conjugate Unconjugated
Target Species Human
Applications WB, IP, Block/Neutralize
Description Human Apolipoprotein E/ApoE Antibody
About Apolipoprotein E and Purified
Apolipoprotein E The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
Images
  Apolipoprotein E Purified R&D Systems antibody anti target:Human host:Rat isotype:IgG2a clone:395004 Detection of Human Apolipoprotein E/ApoE by Western Blot. Western blot shows lysates of human lun...

Detection of Human Apolipoprotein E/ApoE by Western Blot. Western blot shows lysates of human lung tissue and human ovary tissue. PVDF membrane was probed with 0.5 µg/mL of Rat Anti-Human Apolipoprotein E/ApoE Monoclonal Antibody (Catalog # MAB41441) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for Apolipoprotein E/ApoE at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

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Purified Excitation and Emission Spectra