XPG Monoclonal / DyLight 755 / 8H7/XPG

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50366IR (View supplier product page)
Size 0.1 ml
Price $449.00
Antigen XPG
Clone 8H7/XPG
Host Mouse
Isotype IgG2a
Conjugate DyLight 755
Target Species Human
Applications WB, FC, ELISA, IHC
Description Mouse XPG antibody [DyLight 755] reacts with Human
About XPG and DyLight 755
XPG This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra