WRN Polyclonal / DyLight 755 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-471IR (View supplier product page)
Size 100 ul
Price $579.00
Antigen WRN
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 755
Target Species Human
Applications WB, ICC/IF
Description Rabbit WRN antibody reacts with Human [DyLight 755]
About WRN and DyLight 755
WRN This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra