Spectrin beta 3 Monoclonal / PerCP / rSPTBN2/1778

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54441PCP (View supplier product page)
Size 100 μl
Price $429.00
Antigen Spectrin beta 3
Clone rSPTBN2/1778
Host Mouse
Isotype IgG3
Conjugate PerCP
Target Species Human, Mouse, Rat
Applications FC
Description Mouse Spectrin beta 3 antibody [PerCP] detects Human, Mouse, Rat
About Spectrin beta 3 and PerCP
Spectrin beta 3 Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
PerCP Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluor™ 710 are preferred. PerCP is a generic dye that has no sole manufacturer.
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PerCP Excitation and Emission Spectra