Spastin Monoclonal / DyLight 405 / Sp 3G11/1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50302V (View supplier product page)
Size 100 μl
Price $379.00
Antigen Spastin
Clone Sp 3G11/1
Host Mouse
Isotype IgG2a
Conjugate DyLight 405
Target Species Human, Mouse, Rat
Applications WB, ELISA, IHC
Description Mouse Spastin antibody [DyLight 405] reacts with Human, Mouse, Rat
About Spastin and DyLight 405
Spastin This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The use of alternative translational initiation sites in this gene results in a single transcript variant that can produce isoforms that differ in the length of their N-terminus and which thereby differ in the efficiency of their export from the nucleus to the cytoplasm. In addition, alternative splicing results in multiple transcript variants that encode isoforms that differ in other protein regions as well. One isoform of this gene has been shown to be a microtubule-severing enzyme that regulates microtubule abundance, mobility, and plus-end distribution. Mutations in this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq, May 2018]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra