SOD3 Monoclonal / Alexa Fluor 647 / 4GG11G6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-22417AF647 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen SOD3
Clone 4GG11G6
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 647
Target Species Guinea Pig, Human, Mouse, Rat
Applications WB, ELISA, IHC, ICC/IF, IHC-P
Description Detects extracellular SOD approx 35kDa.
About SOD3 and Alexa Fluor 647
SOD3 This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. [provided by RefSeq, Oct 2015]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra