PXR Monoclonal / DyLight 755 / V11P4G11*E7

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50519IR (View supplier product page)
Size 0.1 ml
Price $449.00
Antigen PXR
Clone V11P4G11*E7
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 755
Target Species Zebrafish
Applications WB, ELISA, IHC
Description Mouse PXR/NR1I2 antibody [DyLight 755] reacts with Zebrafish
About PXR and DyLight 755
PXR This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra