PIG3 Monoclonal / Alexa Fluor 405 / 1C9

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-22591AF405 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen PIG3
Clone 1C9
Host Mouse
Isotype IgG2a κ
Conjugate Alexa Fluor 405
Target Species Human
Applications WB, FC, ELISA, ICC/IF
Description PIG3 Antibody (1C9) [Alexa Fluor® 405]
About PIG3 and Alexa Fluor 405
PIG3 The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra