P-Cadherin Monoclonal / Alexa Fluor 405 / MM0508-9V11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-11842AF405 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen P-Cadherin
Clone MM0508-9V11
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Human
Applications WB, FC, IHC, IHC-Fr
About P-Cadherin and Alexa Fluor 405
P-Cadherin This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra