PARP Monoclonal / DyLight 680 / 194C1439

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-27335FR (View supplier product page)
Size 0.1 ml
Price $509.00
Antigen PARP
Clone 194C1439
Host Mouse
Isotype IgG2b κ
Conjugate DyLight 680
Target Species Human
Applications WB, FC
Description This monoclonal antibody specifically detects a 89-kDa cleavage fragment containing the catalytic and auto modification domain.
About PARP and DyLight 680
PARP This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra