p53 Monoclonal / Alexa Fluor 488 / V5P4H6*B3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50231AF488 (View supplier product page)
Size 0.1 ml
Price $459.00
Antigen p53
Clone V5P4H6*B3
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 488
Target Species Zebrafish
Applications WB, ELISA, IHC
Description Mouse p53 antibody [Alexa Fluor 488] reacts with Zebrafish
About p53 and Alexa Fluor 488
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra