Osteocalcin Monoclonal / DyLight 755 / 2H9F11F8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-62801IR (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen Osteocalcin
Clone 2H9F11F8
Host Mouse
Isotype IgG2a
Conjugate DyLight 755
Target Species Bovine, Human, Mouse (Negative), Porcine, Rabbit, Rat
Applications ELISA
Description This product recognizes intact human and bovine osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 15-31 and 20-43 of the native molecule. It does not recognize fragments representing amino acids 1-19 or 7-19.
About Osteocalcin and DyLight 755
Osteocalcin This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra