Mre11 Monoclonal / DyLight 488 / 15B8.1E7.6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-59677G (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Mre11
Clone 15B8.1E7.6
Host Armenian Hamster
Isotype IgG
Conjugate DyLight 488
Target Species Human, Mouse
Applications WB, FC, ICC/IF
About Mre11 and DyLight 488
Mre11 This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra