PDE10A Polyclonal / FITC /

Product Details
Supplier GeneTex
Catalog #: GTX47789 (View supplier product page)
Size 50 μg
Price $319.00
Antigen PDE10A
Clone
Host Rabbit
Isotype IgG
Conjugate FITC
Target Species Human, Mouse, Rat
Applications ICC, IF
Description The Anti-PDE10A antibody from GeneTex is a Rabbit Polyclonal antibody to PDE10A. The Anti-PDE10A antibody Recognizes Human, Mouse, Rat. The Anti-PDE10A antibody has been validated for the following Applications: ICC/IF.
About PDE10A and FITC
PDE10A The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]
FITC Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.
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FITC Excitation and Emission Spectra