CD326 / Vio Blue / HEA-125
CD326 / Vio Blue / HEA-125
Citations:
(4)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-113-266 (View supplier product page) | |
Size | 100 tests in 200 µL | |
Price | $360.00 | |
Antigen | CD326 | |
Clone | HEA-125 | |
Host | Mouse | |
Isotype | IgG1,κappa | |
Conjugate | Vio Blue | |
Target Species | Human | |
Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC | |
Description | Clone HEA-125 recognizes the CD326 antigen, also known as human epithelial antigen (HEA), epithelial cell adhesion molecule (EpCAM), or epithelial-specific antigen (ESA), and is involved in cell adhesion. The CD326 antigen is broadly expressed on the basolateral surface of carcinoma and epithelial cells in tissues or on circulating tumor cells and cancer stem cells, but is not found on melanoma, neuroblastoma, sarcoma, lymphoma, leukemia cells, or normal fibroblasts. |
About CD326 and Vio Blue
CD326 | This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008] | |
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Vio Blue | Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec). |
Citations
PMID 2449234 | ||
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PMID 17062128 | ||
PMID 19696931 | ||
Additional Sources |
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Reviews & Ratings
Vio Blue Excitation and Emission Spectra
$360.00
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