CD20 / PE-Vio615 / LT20
CD20 / PE-Vio615 / LT20
Citations:
(3)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-119-705 (View supplier product page) | |
Size | 30 tests in 60 µL | |
Price | $165.00 | |
Antigen | CD20 | |
Clone | LT20 | |
Host | Mouse | |
Isotype | IgG1,κappa | |
Conjugate | PE-Vio615 | |
Target Species | Human | |
Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC | |
Description | The antibody recognizes the CD20 antigen, a non-glycosylated transmembrane protein of 33–37 kDa that is expressed on B lineage cells from the pre–B cell stage to the B cell lymphoblast stage. The antigen is further expressed on most malignant B cells. CD20 is not found on early B cell progenitors or plasma cells. Oligomers of CD20 form a Ca2+ channel and might function in the regulation of local responses during B cell activation. |
About CD20 and PE-Vio615
CD20 | This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008] | |
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PE-Vio615 | PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594 |
Citations
PMID 12004080 | ||
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PMID 18684866 | ||
PMID 19525224 | ||
Additional Sources |
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Reviews & Ratings
PE-Vio615 Excitation and Emission Spectra
$165.00
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