CD20 / PE-Vio615 / LT20

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-119-705 (View supplier product page)
Size 30 tests in 60 µL
Price $165.00
Antigen CD20
Clone LT20
Host Mouse
Isotype IgG1,κappa
Conjugate PE-Vio615
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Description The antibody recognizes the CD20 antigen, a non-glycosylated transmembrane protein of 33–37 kDa that is expressed on B lineage cells from the pre–B cell stage to the B cell lymphoblast stage. The antigen is further expressed on most malignant B cells. CD20 is not found on early B cell progenitors or plasma cells. Oligomers of CD20 form a Ca2+ channel and might function in the regulation of local responses during B cell activation.
About CD20 and PE-Vio615
CD20 This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
PE-Vio615 PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594
Citations
Reviews & Ratings
PE-Vio615 Excitation and Emission Spectra