Ribosomal Protein S6 / PE / A16009C
Ribosomal Protein S6 / PE / A16009C
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 691803 (View supplier product page) | |
| Size | 25T | |
| Price | $141.00 | |
| Antigen | Ribosomal Protein S6 | |
| Clone | A16009C | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | PE | |
| Target Species | Human, Mouse | |
| Applications | ICS | |
| Description | PE anti-RPS6 |
About Ribosomal Protein S6 and PE
| Ribosomal Protein S6 | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Images
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HEK 293T cells were fixed, permeabilized, and intracellularly stained with anti-RPS6 (clone A16009C) PE (filled histogram) or purified Mouse IgG2b, κ PE isotype control (open histogram). |
Citations
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Reviews & Ratings
PE Excitation and Emission Spectra
$141.00
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