CD160 / Biotin / BY55
CD160 / Biotin / BY55
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 341214 (View supplier product page) | |
| Size | 100 μg | |
| Price | $282.00 | |
| Antigen | CD160 | |
| Clone | BY55 | |
| Host | Mouse | |
| Isotype | IgM κ | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | FC | |
| Description | Biotin anti-human CD160 |
About CD160 and Biotin
| CD160 | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008] |
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Images
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Human peripheral blood lymphocytes were stained with CD8 APC and biotinylated CD160 (clone BY55) (left) or biotinylated mouse IgM, κ isotype control (right), followed by SAV-PE. |
Citations
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Reviews & Ratings
Biotin Excitation and Emission Spectra
$282.00
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