CD357 Monoclonal / PE / DTA-1

Product Details
Supplier Tonbo Biosciences
Catalog #: 50-5874-U025 (View supplier product page)
Size 25 μg
Price $63.00
Antigen CD357
Clone DTA-1
Host Rat
Isotype IgG2b
Conjugate PE
Target Species Mouse
Applications FC
Description PE Anti-Mouse CD357 (GITR) (DTA-1) | Cat. No. 50-5874-U025 | Size 25 µg
About CD357 and PE
CD357 This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra