CD8b.2 Monoclonal / Vio Blue / REA865

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-114-284 (View supplier product page)
Size 150 µg in 1 mL
Price $465.00
Antigen CD8b.2
Clone REA865
Host Human
Isotype IgG1
Conjugate Vio Blue
Target Species Mouse
Applications FC
Description Clone REA865 recognizes the β chain of the mouse CD8 antigen, a single-pass type I membrane protein also known as lymphocyte antigen 3 (Ly-3.2 or Lyt-3.2). The CD8 molecule is composed of two distinct polypeptide chains that pair on the cell surface either as a CD8 αα homodimer or as a CD8 αβ heterodimer. These forms of the CD8 molecule are differentially expressed on functionally distinct CD8+ lymphocyte subsets. The CD8 αβ heterodimer is expressed on cytotoxic T cells and thymocytes. CD8b functions as a co-receptor for the T cell receptor (TCR). | Additional information: Clone REA865 displays negligible binding to Fc receptors.
Citations
PMID 8976201
PMID 11114424
PMID 16356863
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Vio Blue Excitation and Emission Spectra