CD80 Monoclonal / APC-Vio770 / REA983
CD80 Monoclonal / APC-Vio770 / REA983
Citations:
(3)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-116-463 (View supplier product page) | |
Size | 30 µg in 200 µL | |
Price | $120.00 | |
Antigen | CD80 | |
Clone | REA983 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | APC-Vio770 | |
Target Species | Mouse | |
Applications | FC | |
Description | Clone REA983 recognizes the mouse CD80 antigen also known as B7, B7-1, or Ly-53. The 55 kDa member of the Ig superfamily is expressed on activated B cells, macrophages, and dendritic cells. The interaction of CD80 and CD152 (CTLA-4) or CD28 induces T cell proliferation and cytokine production. | Additional information: Clone REA983 displays negligible binding to Fc receptors. |
About CD80 and APC-Vio770
CD80 | The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011] | |
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APC-Vio770 | APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry. |
Citations
PMID 1373896 | ||
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PMID 7512724 | ||
PMID 7519245 | ||
PMID 7540940 | ||
Additional Sources |
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Reviews & Ratings
APC-Vio770 Excitation and Emission Spectra
$120.00
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