CD64 Monoclonal / PE-Vio770 / REA978

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-116-301 (View supplier product page)
Size 30 tests in 60 µL
Price $165.00
Antigen CD64
Clone REA978
Host Human
Isotype IgG1
Conjugate PE-Vio770
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry
Description Clone REA978 recognizes the human CD64 antigen, a high affinity Fc receptor for IgG, also known as FcγRI. CD64 contains three Ig-like domains in its extracellular domain and binds both monomeric and aggregated IgG and contributes to antibody-dependent cellular cytotoxicity (ADCC), phagocytosis, and the clearance of immune complexes. It is constitutively expressed on macrophages, monocytes, and eosinophils and can be up-regulated on neutrophils during infection or after stimulation with IFN-γ and colony-stimulating factors G-CSF and GM-CSF. | Additional information: Clone REA978 displays negligible binding to Fc receptors.
Citations
PMID 2476506
PMID 2955043
PMID 8642575
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PE-Vio770 Excitation and Emission Spectra