CD3e Monoclonal / FITC / REA975

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-116-288 (View supplier product page)
Size 30 tests in 60 µL
Price $95.00
Antigen CD3e
Clone REA975
Host Human
Isotype IgG1
Conjugate FITC
Target Species Human, Mouse
Applications FC
Description Clone REA975 recognizes an intracellular part of the CD3ε chain (activation epitope). CD3ε is a single-pass type I membrane protein, which is a part of the CD3 complex and a subunit of the TCR complex. The CD3 complex mediates signal transduction in several intracellular pathways and has a role in T cell activation and antigen recognition by binding the peptide/MHC antigen complex. CD3ε is expressed on all mature T lymphocytes, NKT cells, and during the development of thymocytes. | Additional information: Clone REA975 displays negligible binding to Fc receptors.
Citations
PMID 2973066
PMID 3478717
PMID 8490660
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FITC Excitation and Emission Spectra