CD326 Monoclonal / PE-Vio615 / HEA-125
CD326 Monoclonal / PE-Vio615 / HEA-125
Citations:
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Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-114-536 (View supplier product page) | |
Size | 100 tests in 200 µL | |
Price | $335.00 | |
Antigen | CD326 | |
Clone | HEA-125 | |
Host | Mouse | |
Isotype | IgG1,κappa | |
Conjugate | PE-Vio615 | |
Target Species | Human | |
Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC | |
Description | Clone HEA-125 recognizes the CD326 antigen, also known as human epithelial antigen (HEA), epithelial cell adhesion molecule (EpCAM), or epithelial-specific antigen (ESA), and is involved in cell adhesion. The CD326 antigen is broadly expressed on the basolateral surface of carcinoma and epithelial cells in tissues or on circulating tumor cells and cancer stem cells, but is not found on melanoma, neuroblastoma, sarcoma, lymphoma, leukemia cells, or normal fibroblasts. |
About CD326 and PE-Vio615
CD326 | This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008] | |
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PE-Vio615 | PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594 |
Citations
PMID 2449234 | ||
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PMID 17062128 | ||
PMID 19696931 | ||
Additional Sources |
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Reviews & Ratings
PE-Vio615 Excitation and Emission Spectra
$335.00
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