CD310 Monoclonal / PE / REA834
CD310 Monoclonal / PE / REA834
Citations:
(3)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-112-772 (View supplier product page) | |
Size | 30 µg in 200 µL | |
Price | $75.00 | |
Antigen | CD310 | |
Clone | REA834 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | PE | |
Target Species | Mouse | |
Applications | FC | |
Description | Clone REA834 recognizes the mouse CD310 antigen, a member of the receptor tyrosine kinase family. This 195 kDa molecule is also known as Flt-4 or VEGFR-3. During early embryogenesis all endothelial cells express CD310, while in the adult tissues CD310 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. CD310 expression is also induced upon tumor angiogenesis. VEGF-C and VEGF-D are ligands for CD310. | Additional information: Clone REA834 displays negligible binding to Fc receptors. |
About CD310 and PE
CD310 | This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008] | |
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PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
PMID 1319394 | ||
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PMID 10887117 | ||
PMID 20697430 | ||
Additional Sources |
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Reviews & Ratings
PE Excitation and Emission Spectra
$75.00
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