FGF-R2 Polyclonal / ATTO 700 /

Product Details
Supplier Stressmarq
Catalog #: SPC-1148D-A700 (View supplier product page)
Size 100 μl
Price $342.00
Antigen FGF-R2
Clone
Host Rabbit
Isotype IgG
Conjugate ATTO 700
Target Species Human, Mouse
Applications WB, Microarray
Description Rabbit Anti-Human FGFR2 Polyclonal
About FGF-R2 and ATTO 700
FGF-R2 The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
ATTO 700 ATTO 700 from ATTO-Tec Gmbh has an excitation peak at 700 nm and an emission peak at 719 nm.
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ATTO 700 Excitation and Emission Spectra