DUX4 Monoclonal / ATTO 700 / P2B1

Product Details
Supplier Stressmarq
Catalog #: SMC-192D-A700 (View supplier product page)
Size 100 μg
Price $341.00
Antigen DUX4
Clone P2B1
Host Mouse
Isotype IgG1
Conjugate ATTO 700
Target Species Human, Mouse
Applications WB, IHC, ICC/IF
Description Mouse Anti-Human DUX4 Monoclonal IgG1
About DUX4 and ATTO 700
DUX4 This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
ATTO 700 ATTO 700 from ATTO-Tec Gmbh has an excitation peak at 700 nm and an emission peak at 719 nm.
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ATTO 700 Excitation and Emission Spectra