CD117 Polyclonal / ATTO 700 /

Product Details
Supplier Stressmarq
Catalog #: SPC-1155D-A700 (View supplier product page)
Size 100 μl
Price $342.00
Antigen CD117
Clone
Host Rabbit
Isotype IgG
Conjugate ATTO 700
Target Species Human, Mouse
Applications WB, Microarray
Description Rabbit Anti-Human c-Kit Polyclonal
About CD117 and ATTO 700
CD117 This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains, a transmembrane region, and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2020]
ATTO 700 ATTO 700 from ATTO-Tec Gmbh has an excitation peak at 700 nm and an emission peak at 719 nm.
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ATTO 700 Excitation and Emission Spectra