SHANK3 Monoclonal / ATTO 680 / S69-46

Product Details
Supplier Stressmarq
Catalog #: SMC-336D-A680 (View supplier product page)
Size 100 μg
Price $341.00
Antigen SHANK3
Clone S69-46
Host Mouse
Isotype IgG2b
Conjugate ATTO 680
Target Species Human, Mouse, Rat
Applications WB, IHC, IP, ICC/IF, Microarray
Description Mouse Anti-Rat SHANK3 Monoclonal IgG2b
About SHANK3 and ATTO 680
SHANK3 This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012]
ATTO 680 ATTO 680 from ATTO-Tec Gmbh has an excitation peak at 680 nm and an emission peak at 700 nm.
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ATTO 680 Excitation and Emission Spectra