Cyclin D1 Polyclonal / ATTO 680 /

Product Details
Supplier Stressmarq
Catalog #: SPC-731D-A680 (View supplier product page)
Size 100 μg
Price $341.00
Antigen Cyclin D1
Clone
Host Rabbit
Isotype IgG
Conjugate ATTO 680
Target Species Human, Rat
Applications WB, IHC
Description Rabbit Anti-Human Cyclin D1 Polyclonal
About Cyclin D1 and ATTO 680
Cyclin D1 The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of human cancers. [provided by RefSeq, Dec 2019]
ATTO 680 ATTO 680 from ATTO-Tec Gmbh has an excitation peak at 680 nm and an emission peak at 700 nm.
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ATTO 680 Excitation and Emission Spectra