MKK3 Polyclonal / ATTO 565 /

Product Details
Supplier Stressmarq
Catalog #: SPC-1168D-A565 (View supplier product page)
Size 100 μl
Price $342.00
Antigen MKK3
Clone
Host Rabbit
Isotype IgG
Conjugate ATTO 565
Target Species Human, Mouse
Applications WB, Microarray
Description Rabbit Anti-Human MEK3 Polyclonal
About MKK3 and ATTO 565
MKK3 The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]
ATTO 565 ATTO 565 from ATTO-Tec Gmbh has an excitation peak at 563 nm and an emission peak at 592 nm.
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ATTO 565 Excitation and Emission Spectra