DUSP6 Polyclonal / ATTO 565 /

Product Details
Supplier Stressmarq
Catalog #: SPC-1127D-A565 (View supplier product page)
Size 100 μl
Price $342.00
Antigen DUSP6
Clone
Host Rabbit
Isotype IgG
Conjugate ATTO 565
Target Species Human, Mouse
Applications WB, Microarray
Description Rabbit Anti-Human DUSP6 Polyclonal
About DUSP6 and ATTO 565
DUSP6 The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]
ATTO 565 ATTO 565 from ATTO-Tec Gmbh has an excitation peak at 563 nm and an emission peak at 592 nm.
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ATTO 565 Excitation and Emission Spectra