MDM2 Polyclonal / ATTO 390 /

Product Details
Supplier Stressmarq
Catalog #: SPC-778D-A390 (View supplier product page)
Size 100 μg
Price $392.00
Antigen MDM2
Clone
Host Rabbit
Isotype IgG
Conjugate ATTO 390
Target Species Human, Mouse, Rat
Applications IHC, ICC/IF
Description Rabbit Anti-Human MDM2 Polyclonal
About MDM2 and ATTO 390
MDM2 This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
ATTO 390 ATTO 390 from ATTO-TEC has an excitation peak at 390 nm and an emission peak at 448 nm. It is a novel fluorescent label with a coumarin structure. Characteristic features of the label are high fluorescence quantum yield, large Stokes-shift, good photo-stability, and low molecular weight.
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ATTO 390 Excitation and Emission Spectra