ABCG2 Polyclonal / ATTO 390 /

Product Details
Supplier Stressmarq
Catalog #: SPC-1317D-A390 (View supplier product page)
Size 100 μl
Price $340.00
Antigen ABCG2
Clone
Host Rabbit
Isotype IgG
Conjugate ATTO 390
Target Species Human
Applications WB, IHC
Description Rabbit Anti-Human ABCG2 Polyclonal
About ABCG2 and ATTO 390
ABCG2 The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
ATTO 390 ATTO 390 from ATTO-TEC has an excitation peak at 390 nm and an emission peak at 448 nm. It is a novel fluorescent label with a coumarin structure. Characteristic features of the label are high fluorescence quantum yield, large Stokes-shift, good photo-stability, and low molecular weight.
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ATTO 390 Excitation and Emission Spectra