HspB8 Monoclonal / PE / 3C12-H11

Product Details
Supplier Stressmarq
Catalog #: SMC-187D-RPE (View supplier product page)
Size 100 μg
Price $380.00
Antigen HspB8
Clone 3C12-H11
Host Mouse
Isotype IgG1 κ
Conjugate PE
Target Species Human, Mouse, Rat
Applications WB, ELISA, IHC, ICC/IF
Description Mouse Anti-Human HSP22 Monoclonal IgG1 Kappa
About HspB8 and PE
HspB8 The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra