ABCC8 Monoclonal / ATTO 655 / S323A-31

Product Details
Supplier Stressmarq
Catalog #: SMC-432D-A655 (View supplier product page)
Size 100 μg
Price $341.00
Antigen ABCC8
Clone S323A-31
Host Mouse
Isotype IgG1
Conjugate ATTO 655
Target Species Mouse, Rat
Applications WB, ICC/IF
Description Mouse Anti-Rat SUR1 and SUR2B Monoclonal IgG1
About ABCC8 and ATTO 655
ABCC8 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations in the ABCC8 gene and deficiencies in the encoded protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2020]
ATTO 655 ATTO 655 from ATTO-Tec Gmbh has an excitation peak at 663 nm and an emission peak at 684 nm.
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ATTO 655 Excitation and Emission Spectra