Notch 1 Monoclonal / ATTO 594 / N253/32 (Formerly sold as S253-32)
Notch 1 Monoclonal / ATTO 594 / N253/32 (Formerly sold as S253-32)
Product Details
| Supplier | Stressmarq | |
|---|---|---|
| Catalog #: | SMC-430D-A594 (View supplier product page) | |
| Size | 100 μg | |
| Price | $391.00 | |
| Antigen | Notch 1 | |
| Clone | N253/32 (Formerly sold as S253-32) | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | ATTO 594 | |
| Target Species | Human, Mouse, Rat | |
| Applications | ICC/IF, IHC | |
| Description | Mouse Anti-Mouse Notch1 Monoclonal IgG1 |
About Notch 1 and ATTO 594
| Notch 1 | This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016] | |
|---|---|---|
| ATTO 594 | ATTO 594 from ATTO-TEC has an excitation peak at 601 nm and an emission peak at 627 nm. ATTO 594 is a novel fluorescent label belonging to the class of rhodamine dyes. Characteristic features of the label are strong absorption, high fluorescence quantum yield, high thermal and photo-stability, and excellent water solubility. Thus ATTO 594 is highly suitable for single-molecule detection applications and high-resolution microscopy such as PALM, dSTORM, STED etc. Additionally the dye highly qualifies to be applied in flow cytometry (FACS), fluorescence in-situ hybridization (FISH) and many more. ATTO 594 is very hydrophilic and shows a very good water solubility. After coupling to a substrate the label carries a net electrical charge of -1. |
Citations
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Reviews & Ratings
ATTO 594 Excitation and Emission Spectra
$391.00
Supplier Page
Supplier Page
