KCNQ1 Monoclonal / ATTO 594 / N37A/10 (Formerly sold as S37A-10)

Product Details
Supplier Stressmarq
Catalog #: SMC-307D-A594 (View supplier product page)
Size 100 μg
Price $391.00
Antigen KCNQ1
Clone N37A/10 (Formerly sold as S37A-10)
Host Mouse
Isotype IgG1
Conjugate ATTO 594
Target Species Hamster, Human, Mouse, Rat
Applications IHC, ICC/IF
Description Mouse Anti-Human KCNQ1 Monoclonal IgG1
About KCNQ1 and ATTO 594
KCNQ1 This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
ATTO 594 ATTO 594 from ATTO-TEC has an excitation peak at 601 nm and an emission peak at 627 nm. ATTO 594 is a novel fluorescent label belonging to the class of rhodamine dyes. Characteristic features of the label are strong absorption, high fluorescence quantum yield, high thermal and photo-stability, and excellent water solubility. Thus ATTO 594 is highly suitable for single-molecule detection applications and high-resolution microscopy such as PALM, dSTORM, STED etc. Additionally the dye highly qualifies to be applied in flow cytometry (FACS), fluorescence in-situ hybridization (FISH) and many more. ATTO 594 is very hydrophilic and shows a very good water solubility. After coupling to a substrate the label carries a net electrical charge of -1.
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ATTO 594 Excitation and Emission Spectra