p57Kip2 Monoclonal / CF488A / KP10 KIP2/880

Product Details
Supplier Biotium
Catalog #: BNC881015-100 (View supplier product page)
Size 100 μl
Price $199.00
Antigen p57Kip2
Clone KP10 KIP2/880
Host Mouse
Isotype IgG
Conjugate CF488A
Target Species Human, Mouse
Applications
Description p57 / KIP2(KP10 + KIP2/880), CF488A conjugate, 0.1mg/mL
About p57Kip2 and CF488A
p57Kip2 This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
CF488A CF®488A from Biotium is a fluorophore with an excitation peak at 490 nm and an emission peak at 515 nm. It is spectrally similar to Fluorescein, Alexa Fluor™ 488 and DyLight™ 488. It can be use in fluorescence microscopy and flow cytometry. In microscopy, CF®488A has been specifically validated for STORM, STED, Structured Illumination (SIM), 2-Photon microscopy and TIRF.
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CF488A Excitation and Emission Spectra