p57Kip2 Monoclonal / CF405S / KIP2/880

Product Details
Supplier Biotium
Catalog #: BNC040880-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen p57Kip2
Clone KIP2/880
Host Mouse
Isotype IgG2b κ
Conjugate CF405S
Target Species Human, Mouse
Applications IHC, IHC FFPE
Description p57 / KIP2(KIP2/880), CF405S conjugate, 0.1mg/mL
About p57Kip2 and CF405S
p57Kip2 This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
CF405S CF®405S from Biotium is a fluorophore with an excitation peak at 404 nm and an emission peak at 431 nm. It is spectrally similar to Alexa Fluor™ 405. It can be use in fluorescence microscopy, specifically its been validated in Structured Illumination (SIM), and flow cytometry. However, in flow cytometry, superior alternatives are Brilliant™ Violet 421, SuperNova v428 and StarBright Violet 440.
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CF405S Excitation and Emission Spectra