Bcl-6 Monoclonal / CF543 / BCL6/850

Product Details
Supplier Biotium
Catalog #: BNC430850-500 (View supplier product page)
Size 500 μl
Price $470.00
Antigen Bcl-6
Clone BCL6/850
Host Mouse
Isotype IgG1 κ
Conjugate CF543
Target Species Human, Mouse
Applications IF, IHC-P, FC
Description Bcl-6 Monoclonal Mouse Antibody (BCL6/850)
About Bcl-6 and CF543
Bcl-6 The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
CF543 CF®543 from Biotium is a fluorophore with an excitation peak at 541 nm and an emission peak at 560 nm. It can be useful in both fluorescence microscopy and flow cytometry.
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CF543 Excitation and Emission Spectra