alpha Fetoprotein Monoclonal / CF488A / C2

Product Details
Supplier Biotium
Catalog #: BNC880523-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen alpha Fetoprotein
Clone C2
Host Mouse
Isotype IgG1 κ
Conjugate CF488A
Target Species Human, Mouse
Applications IHC, IHC FFPE
Description AFP (Alpha Fetoprotein)(C2), CF488A conjugate, 0.1mg/mL
About alpha Fetoprotein and CF488A
alpha Fetoprotein This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]
CF488A CF®488A from Biotium is a fluorophore with an excitation peak at 490 nm and an emission peak at 515 nm. It is spectrally similar to Fluorescein, Alexa Fluor™ 488 and DyLight™ 488. It can be use in fluorescence microscopy and flow cytometry. In microscopy, CF®488A has been specifically validated for STORM, STED, Structured Illumination (SIM), 2-Photon microscopy and TIRF.
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CF488A Excitation and Emission Spectra