p27 KIP 1 Monoclonal / CF555 / KIP1/769

Product Details
Supplier Biotium
Catalog #: BNC550769-500 (View supplier product page)
Size 500 μl
Price $470.00
Antigen p27 KIP 1
Clone KIP1/769
Host Mouse
Isotype IgG1 κ
Conjugate CF555
Target Species Human, Monkey, Mouse, Rat
Applications IF, IHC-P, FC, WB
Description p27 / KIP1 Monoclonal Mouse Antibody (KIP1/769)
About p27 KIP 1 and CF555
p27 KIP 1 This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
CF555 CF®555 from Biotium is a fluorophore with an excitation peak at 555 nm and an emission peak at 565 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 555, ATTO 550 and DyLight™ 550. In Flow Cytometry, R-PE is a brighter alternative to CF®555. In microscopy, it has been validated for use in super-resolution imaging by STORM.
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CF555 Excitation and Emission Spectra