Cyclin D1 Monoclonal / CF680 / DCS-6

Product Details
Supplier Biotium
Catalog #: BNC800007-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen Cyclin D1
Clone DCS-6
Host Mouse
Isotype IgG2a κ
Conjugate CF680
Target Species Human, Monkey, Mouse, Rat
Applications IF, IHC-P, FC, WB
Description Cyclin D1 Monoclonal Mouse Antibody (DCS-6)
About Cyclin D1 and CF680
Cyclin D1 The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of human cancers. [provided by RefSeq, Dec 2019]
CF680 CF®680 from Biotium is a fluorophore with an excitation peak at 681 nm and an emission peak at 698 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

CF680 Excitation and Emission Spectra