ZAP70 Monoclonal / CF660R / ZAP70/528 2F3.2

Product Details
Supplier Biotium
Catalog #: BNC611137-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen ZAP70
Clone ZAP70/528 2F3.2
Host Mouse
Isotype IgG
Conjugate CF660R
Target Species Human
Applications IF, IHC-P, FC
Description ZAP70 Monoclonal Mouse Antibody (ZAP70/528 + 2F3.2)
About ZAP70 and CF660R
ZAP70 This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
CF660R CF®660R from Biotium is a fluorophore with an excitation peak at 662 nm and an emission peak at 682 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 660.
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CF660R Excitation and Emission Spectra