Spectrin beta 3 Monoclonal / CF770 / SPTBN2/1583

Product Details
Supplier Biotium
Catalog #: BNC701583-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen Spectrin beta 3
Clone SPTBN2/1583
Host Mouse
Isotype IgG2b κ
Conjugate CF770
Target Species Human
Applications IF, FC, WB
Description Spectrin Beta-III Monoclonal Mouse Antibody (SPTBN2/1583)
About Spectrin beta 3 and CF770
Spectrin beta 3 Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
CF770 CF®770 from Biotium is a fluorophore with an excitation peak at 770 nm and an emission peak at 797 nm. It is spectrally similar to DyeLight 800 and IRDye® 800CW.
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CF770 Excitation and Emission Spectra