PD-1 Monoclonal / CF680R / PDCD1/922

Product Details
Supplier Biotium
Catalog #: BNC810922-500 (View supplier product page)
Size 500 μl
Price $470.00
Antigen PD-1
Clone PDCD1/922
Host Mouse
Isotype IgG1 κ
Conjugate CF680R
Target Species Human
Applications IF, IHC-P, FC
Description PD1 / PDCD1 / CD279 Monoclonal Mouse Antibody (PDCD1/922)
About PD-1 and CF680R
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
CF680R CF®680R from Biotium is a fluorophore with an excitation peak at 680 nm and an emission peak at 701 nm. It can be useful in both fluorescence microscopy and flow cytometry. For microscopy, CF®680R has been specifically validated in super-resolution imaging by STORM, STED and 2-Photon microscopy. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.
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CF680R Excitation and Emission Spectra