NOX4 Monoclonal / CF405S / NOX4/1245

Product Details
Supplier Biotium
Catalog #: BNC041245-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen NOX4
Clone NOX4/1245
Host Mouse
Isotype IgG2b κ
Conjugate CF405S
Target Species Human
Applications
Description NOX4 / NADPH Oxidase 4 (NOX4/1245), CF405S conjugate, 0.1mg/mL
About NOX4 and CF405S
NOX4 This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
CF405S CF®405S from Biotium is a fluorophore with an excitation peak at 404 nm and an emission peak at 431 nm. It is spectrally similar to Alexa Fluor™ 405. It can be use in fluorescence microscopy, specifically its been validated in Structured Illumination (SIM), and flow cytometry. However, in flow cytometry, superior alternatives are Brilliant™ Violet 421, SuperNova v428 and StarBright Violet 440.
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CF405S Excitation and Emission Spectra